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pentobarbital decreases amounts of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent CYP3A4 inducers can cut down panobinostat stages by ~70% and bring about remedy failure.pentobarbital will reduce the level or impact of bazedoxifene/conjugated estrogens by affecting hepatic/intestinal enzyme CYP3A4 met